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4-hydroxybenzoic acid; p-hydroxybenzoic acid; hydroxybenzoic acid; 4-hydroxy benzoic acid


Name(s) 4-hydroxybenzoic acid; p-hydroxybenzoic acid; hydroxybenzoic acid; 4-hydroxy benzoic acid
Scientific name(s) p-hydroxybenzoic acid; 4-carboxyphenol; p-salicylic acid; benzoic acid, 4-hydroxy-; para-hydroxybenzoic acid; benzoic acid, p-hydroxy-
Formula C7H6O3
Molecular mass 138.122
IUPAC name 4-hydroxybenzoic acid
INCHI InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)
SMILE OC(=O)C1=CC=C(O)C=C1
CAS ID 99-96-7
PubChem ID 135
DrugBank ID DB04242
CHEBI ID Not available
Description Isolated from many plants, free and combined. Alkyl esters of 4-hydroxybenzoic acid (see below) are used as food and cosmetic preservatives, mainly in their Na salt form, which makes them more water soluble. They are active at low concentrations and more pH-independent than the commonly used Benzoic acid <ht>DVN38-Z</ht> and 2,4-Hexadienoic acid <ht>GMZ10-P</ht>. The taste is more detectable than for those preservatives. Effectiveness increases with chain length of the alcohol, but for some microorganisms this reduces cell permeability and thus counteracts the increased efficiency. 4-Hydroxybenzoic acid is found in many foods, some of which are chicory, corn, rye, and black huckleberry.